The Enzyme Database

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Accepted name: acetone carboxylase
Reaction: acetone + CO2 + ATP + 2 H2O = acetoacetate + AMP + 2 phosphate
Systematic name: acetone:carbon-dioxide ligase (AMP-forming)
Comments: Requires Mg2+ and ATP. The enzyme from Xanthobacter sp. strain Py2 also carboxylates butan-2-one to 3-oxopentanoate.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 189258-15-9
1.  Sluis, M.K. and Ensign, S.A. Purification and characterization of acetone carboxylase from Xanthobacter strain Py2. Proc. Natl. Acad. Sci. USA 94 (1997) 8456–8461. [DOI] [PMID: 9237998]
[EC created 2001]

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