EC |
6.3.4.7 |
Accepted name: |
ribose-5-phosphate—ammonia ligase |
Reaction: |
ATP + ribose 5-phosphate + NH3 = ADP + phosphate + 5-phosphoribosylamine |
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For diagram of ribose activation, click here |
Other name(s): |
5-phosphoribosylamine synthetase; ribose 5-phosphate aminotransferase; ammonia-ribose 5-phosphate aminotransferase |
Systematic name: |
ribose-5-phosphate:ammonia ligase (ADP-forming) |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 9082-52-4 |
References: |
1. |
Reem, G.H. Enzymatic synthesis of 5′-phosphoribosylamine from ribose 5-phosphate and ammonia, an alternate first step in purine biosynthesis. J. Biol. Chem. 243 (1968) 5695–5701. [PMID: 5699059] |
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[EC 6.3.4.7 created 1972] |
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