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2 ATP + N-acetyl- L-aspartate + 2 L-glutamate = 2 ADP + 2 phosphate + N-acetyl- L-aspartyl- L-glutamyl- L-glutamate
N-acetylaspartylglutamylglutamate synthetase; NAAG(2) synthase; NAAG synthetase II; NAAGS-II; RIMKLA ( gene name) ( ambiguous)
N-acetyl- L-aspartate: L-glutamate ligase (ADP, N-acetyl- L-aspartyl- L-glutamyl- L-glutamate-forming)
Comments: The enzyme, found in mammals, also has the activity of
EC 188.8.131.52, N-acetylaspartylglutamate synthase.
Links to other databases:
BRENDA, EXPASY, KEGG, MetaCyc
Lodder-Gadaczek, J., Becker, I., Gieselmann, V., Wang-Eckhardt, L. and Eckhardt, M.
N-acetylaspartylglutamate synthetase II synthesizes N-acetylaspartylglutamylglutamate. J. Biol. Chem. 286 (2011) 16693–16706. [ DOI] [PMID: 21454531]
[EC 184.108.40.206 created 2014]
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