| EC |
6.3.1.5 |
| Accepted name: |
NAD+ synthase |
| Reaction: |
ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+ |
| Other name(s): |
NAD synthetase; NAD synthase; nicotinamide adenine dinucleotide synthetase; diphosphopyridine nucleotide synthetase |
| Systematic name: |
deamido-NAD+:ammonia ligase (AMP-forming) |
| Comments: |
L-Glutamine also acts, more slowly, as amido-donor [cf. EC 6.3.5.1]. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9032-69-3 |
| References: |
| 1. |
Spencer, R.L. and Preiss, J. Biosynthesis of diphosphopyridine nucleotide. The purification and the properties of diphosphopyridine nucleotide synthetase from Escherichia coli B. J. Biol. Chem. 242 (1967) 385–392. [PMID: 4290215] |
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| [EC 6.3.1.5 created 1972] |
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