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Your query returned 1 entry. Printable version
EC | 6.2.1.68 | ||
Accepted name: | L-glutamate—[L-glutamyl-carrier protein] ligase | ||
Reaction: | ATP + L-glutamate + holo-[L-glutamyl-carrier protein] = AMP + diphosphate + L-glutamyl-[L-glutamyl-carrier protein] (overall reaction) (1a) ATP + L-glutamate = diphosphate + (L-glutamyl)adenylate (1b) (L-glutamyl)adenylate + holo-[L-glutamyl-carrier protein] = AMP + L-glutamyl-[L-glutamyl-carrier protein] |
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Other name(s): | ambE (gene name) | ||
Systematic name: | L-glutamate:[L-glutamyl-carrier protein] ligase (AMP-forming) | ||
Comments: | The adenylation domain of the enzyme catalyses the activation of L-glutamate to (L-glutamyl)adenylate, followed by the transfer of the activated compound to the free thiol of a phosphopantetheine arm of a peptidyl-carrier protein domain. The peptidyl-carrier protein domain may be part of the same protein, or of a different protein. This activity is often found as part of a larger non-ribosomal peptide synthase. | ||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||
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