|
Your query returned 1 entry. Printable version
EC | 6.2.1.65 | ||||
Accepted name: | salicylate—CoA ligase | ||||
Reaction: | ATP + salicylate + CoA = AMP + diphosphate + 2-hydroxybenzoyl-CoA (overall reaction) (1a) ATP + salicylate = diphosphate + (2-hydroxybenzoyl)adenylate (1b) (2-hydroxybenzoyl)adenylate + CoA = AMP + 2-hydroxybenzoyl-CoA |
||||
Glossary: | 2-hydroxybenzoyl-CoA = salicyloyl-CoA | ||||
Other name(s): | sdgA (gene name) | ||||
Systematic name: | salicylate:CoA ligase (AMP-forming) | ||||
Comments: | The enzyme, characterized from the bacteria Thauera aromatica and Streptomyces sp. WA46, participates in a salicylate degradation pathway. It activates salicylate by its adenylation to (2-hydroxybenzoyl)adenylate, followed by the transfer of the activated compound to coenzyme A. | ||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||
References: |
| ||||