The Enzyme Database

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EC 6.2.1.25     
Accepted name: benzoate—CoA ligase
Reaction: ATP + benzoate + CoA = AMP + diphosphate + benzoyl-CoA
For diagram of Benzoyl-CoA catabolism, click here
Other name(s): benzoate—coenzyme A ligase; benzoyl-coenzyme A synthetase; benzoyl CoA synthetase (AMP forming)
Systematic name: benzoate:CoA ligase (AMP-forming)
Comments: Also acts on 2-, 3- and 4-fluorobenzoate, but only very slowly on the corresponding chlorobenzoates.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, UM-BBD, CAS registry number: 95329-17-2
References:
1.  Hutber, G.N. and Ribbons, D.W. Involvement of coenzyme-A esters in the metabolism of benzoate and cyclohexanecarboxylate by Rhodopseudomonas palustris. J. Gen. Microbiol. 129 (1983) 2413–2420.
2.  Schennen, U., Braun, K. and Knackmuss, H.-J. Anaerobic degradation of 2-fluorobenzoate by benzoate-degrading, denitrifying bacteria. J. Bacteriol. 161 (1985) 321–325. [PMID: 2857161]
[EC 6.2.1.25 created 1989]
 
 


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