| EC |
6.2.1.10 |
| Accepted name: |
carboxylic acid—CoA ligase (GDP-forming) |
| Reaction: |
GTP + a carboxylate + CoA = GDP + phosphate + acyl-CoA |
| Other name(s): |
acyl-CoA synthetase (GDP-forming); acyl coenzyme A synthetase (guanosine diphosphate forming) |
| Systematic name: |
carboxylic acid:CoA ligase (GDP-forming) |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 37318-59-5 |
| References: |
| 1. |
Rossi, C.R. and Gibson, D.M. Activation of fatty acids by a guanosine triphosphate-specific thiokinase from liver mitochondria. J. Biol. Chem. 239 (1964) 1694–1699. [PMID: 14213337] |
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| [EC 6.2.1.10 created 1972, modified 2011] |
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