The Enzyme Database

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EC 5.4.99.9     
Accepted name: UDP-galactopyranose mutase
Reaction: UDP-α-D-galactopyranose = UDP-α-D-galactofuranose
For diagram of UDP-glucose, UDP-galactose and UDP-glucuronate biosynthesis, click here
Other name(s): UGM; UDP-D-galactopyranose furanomutase
Systematic name: UDP-α-D-galactopyranose furanomutase
Comments: A flavoenzyme which generates UDP-α-D-glactofuranose required for cell wall formation in bacteria, fungi, and protozoa.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 174632-18-9
References:
1.  Trejo, A.G., Chittenden, G.J.F., Buchanan, J.G. and Baddiley, J. Uridine diphosphate α-D-galactofuranose, an intermediate in the biosynthesis of galactofuranosyl residues. Biochem. J. 117 (1970) 637–639. [PMID: 5419754]
2.  Karunan Partha, S., Bonderoff, S.A., van Straaten, K.E. and Sanders, D.A. Expression, purification and preliminary X-ray crystallographic analysis of UDP-galactopyranose mutase from Deinococcus radiodurans. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 65 (2009) 843–845. [PMID: 19652355]
3.  Dhatwalia, R., Singh, H., Oppenheimer, M., Karr, D.B., Nix, J.C., Sobrado, P. and Tanner, J.J. Crystal structures and small-angle x-ray scattering analysis of UDP-galactopyranose mutase from the pathogenic fungus Aspergillus fumigatus. J. Biol. Chem. 287 (2012) 9041–9051. [PMID: 22294687]
4.  van Straaten, K.E., Routier, F.H. and Sanders, D.A. Towards the crystal structure elucidation of eukaryotic UDP-galactopyranose mutase. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 68 (2012) 455–459. [PMID: 22505419]
[EC 5.4.99.9 created 1984, modified 2012]
 
 


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