The Enzyme Database

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EC 5.4.99.49     
Accepted name: glutinol synthase
Reaction: (3S)-2,3-epoxy-2,3-dihydrosqualene = glutinol
For diagram of friedelin, glutinol, isomultiflorenol and taraxerol biosynthesis, click here
Systematic name: (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, glutinol-forming)
Comments: The enzyme from Kalanchoe daigremontiana also gives traces of other triterpenoids.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Wang, Z., Yeats, T., Han, H. and Jetter, R. Cloning and characterization of oxidosqualene cyclases from Kalanchoe daigremontiana: enzymes catalyzing up to 10 rearrangement steps yielding friedelin and other triterpenoids. J. Biol. Chem. 285 (2010) 29703–29712. [PMID: 20610397]
[EC 5.4.99.49 created 2011]
 
 


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