ExplorEnz: EC 5.4.1.2

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5.4.1.2

Accepted name:

precorrin-8X methylmutase

Reaction:

precorrin-8X = hydrogenobyrinate

For diagram of corrin biosynthesis (part 4), click here

Other name(s):

precorrin isomerase; hydrogenobyrinic acid-binding protein

Systematic name:

precorrin-8X 11,12-methylmutase

Links to other databases:

BRENDA, EXPASY, KEGG, METACYC, PDB, CAS registry number: 138238-71-8

References:

1.	Thibaut, D., Couder, M., Famechon, A., Debussche, L., Cameron, B., Crouzet, J., Blanche, F. The final step in the biosynthesis of hydrogenobyrinic acid is catalyzed by the cobH gene product with precorrin-8X as the substrate. J. Bacteriol. 174 (1992) 1043–1049. [PMID: 1732194]
2.	Roth, J.R., Lawrence, J.G., Rubenfield, M., Kieffer-Higgins, S., Church, G.M. Characterization of the cobalamin (vitamin B₁₂) biosynthetic genes of Salmonella typhimurium. J. Bacteriol. 175 (1993) 3303–3316. [PMID: 8501034]
3.	Roessner, C.A., Warren, M.J., Santander, P.J., Atshaves, B.P., Ozaki, S., Stolowich, N.J., Iida, K., Scott, A.I. Expression of Salmonella typhimurium enzymes for cobinamide synthesis. Identification of the 11-methyl and 20-methyl transferases of corrin biosynthesis. FEBS Lett. 301 (1992) 73–78. [PMID: 1451790]
4.	Crouzet, J., Cameron, B., Cauchois, L., Rigault, S., Rouyez, M.C., Blanche, F. , Thibaut D., Debussche, L. Genetic and sequence analysis of an 8.7-kilobase Pseudomonas denitrificans fragment carrying eight genes involved in transformation of precorrin-2 to cobyrinic acid. J. Bacteriol. 172 (1990) 5980–5990. [PMID: 2211521]

[EC 5.4.1.2 created 1999]