The Enzyme Database

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EC 5.3.1.16     
Accepted name: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase
Reaction: 1-(5-phospho-β-D-ribosyl)-5-[(5-phospho-β-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylamino)methylideneamino]-1-(5-phospho-β-D-ribosyl)imidazole-4-carboxamide
For diagram of histidine biosynthesis (early stages), click here
Other name(s): N-(5′-phospho-D-ribosylformimino)-5-amino-1-(5′′-phosphoribosyl)-4-imidazolecarboxamide isomerase; phosphoribosylformiminoaminophosphoribosylimidazolecarboxamide isomerase; N-(phosphoribosylformimino) aminophosphoribosylimidazolecarboxamide isomerase; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide ketol-isomerase; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide aldose-ketose-isomerase
Systematic name: 1-(5-phospho-β-D-ribosyl)-5-[(5-phospho-β-D-ribosylamino)methylideneamino]imidazole-4-carboxamide aldose-ketose-isomerase
Comments: Involved in histidine biosynthesis.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 37318-43-7
References:
1.  Margolies, M.N. and Goldberger, R.F. Isolation of the fourth (isomerase) of histidine biosynthesis from Salmonella typhimurium. J. Biol. Chem. 241 (1966) 3262–3269. [PMID: 5330429]
[EC 5.3.1.16 created 1972, modified 2000]
 
 


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