The Enzyme Database

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EC 4.4.1.9     
Accepted name: L-3-cyanoalanine synthase
Reaction: L-cysteine + hydrogen cyanide = L-3-cyanoalanine + hydrogen sulfide
Other name(s): β-cyanoalanine synthase; β-cyanoalanine synthetase; β-cyano-L-alanine synthase; L-cysteine hydrogen-sulfide-lyase (adding HCN)
Systematic name: L-cysteine hydrogen-sulfide-lyase (adding hydrogen cyanide; L-3-cyanoalanine-forming)
Comments: Contains pyridoxal phospate.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 9059-53-4
References:
1.  Akopyan, T.N., Braunstein, A.E. and Goryachenkova, E.V. β-Cyanoalanine synthase: purification and characterization. Proc. Natl. Acad. Sci. USA 72 (1975) 1617–1621. [PMID: 1055433]
2.  Castric, P.A. and Conn, E.E. Formation of β-cyanoalanine by O-acetylserine sulfhydrylase. J. Bacteriol. 108 (1971) 132–136. [PMID: 5001194]
3.  Hendrickson, H.R. The β-cyanoalanine synthase of blue lupine. Fed. Proc. 27 (1968) 593.
4.  Hendrickson, H.R. and Conn, E.E. Cyanide metabolism in higher plants. IV. Purification and properties of the β-cyanoalanine synthase of blue lupine. J. Biol. Chem. 244 (1969) 2632–2640. [PMID: 5769995]
[EC 4.4.1.9 created 1972, deleted 1976, reinstated 1978]
 
 


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