The Enzyme Database

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EC 4.4.1.10     
Accepted name: cysteine lyase
Reaction: L-cysteine + sulfite = L-cysteate + hydrogen sulfide
For diagram of taurine biosynthesis, click here
Other name(s): cysteine (sulfite) lyase; L-cysteine hydrogen-sulfide-lyase (adding sulfite)
Systematic name: L-cysteine hydrogen-sulfide-lyase (adding sulfite; L-cysteate-forming)
Comments: A pyridoxal-phosphate protein. Can use a second molecule of cysteine (producing lanthionine), or other alkyl thiols, as a replacing agent.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 9079-86-1
References:
1.  Tolosa, E.A., Chepurnova, N.K., Khomutov, R.M. and Severin, E.S. Reactions catalysed by cysteine lyase from the yolk sac of chicken embryo. Biochim. Biophys. Acta 171 (1969) 369–371. [DOI] [PMID: 5813025]
[EC 4.4.1.10 created 1972]
 
 


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