| EC |
4.3.99.4 |
| Accepted name: |
choline trimethylamine-lyase |
| Reaction: |
choline = trimethylamine + acetaldehyde |
| Other name(s): |
cutC (gene name) |
| Systematic name: |
choline trimethylamine-lyase (acetaldehyde-forming) |
| Comments: |
The enzyme utilizes a glycine radical to break the C-N bond in choline. Found in choline-degrading anaerobic bacteria. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Craciun, S. and Balskus, E.P. Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme. Proc. Natl. Acad. Sci. USA 109 (2012) 21307–21312. [DOI] [PMID: 23151509] |
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| [EC 4.3.99.4 created 2013] |
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