The Enzyme Database

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EC 4.3.2.3     
Accepted name: ureidoglycolate lyase
Reaction: (S)-ureidoglycolate = glyoxylate + urea
For diagram of AMP catabolism, click here
Other name(s): ureidoglycolatase (ambiguous); ureidoglycolase (ambiguous); ureidoglycolate hydrolase (misleading); (S)-ureidoglycolate urea-lyase
Systematic name: (S)-ureidoglycolate urea-lyase (glyoxylate-forming)
Comments: This microbial enzyme is involved in the degradation of ureidoglycolate, an intermediate of purine degradation. Not to be confused with EC 3.5.1.116, ureidoglycolate amidohydrolase, which releases ammonia rather than urea.
Links to other databases: BRENDA, EXPASY, GTD, KEGG, MetaCyc, CAS registry number: 9014-57-7
References:
1.  Trijbels, F. and Vogels, G.D. Allantoate and ureidoglycolate degradation by Pseudomonas aeruginosa. Biochim. Biophys. Acta 132 (1967) 115–126. [PMID: 6030341]
2.  Werner, A.K., Romeis, T. and Witte, C.P. Ureide catabolism in Arabidopsis thaliana and Escherichia coli. Nat. Chem. Biol. 6 (2010) 19–21. [PMID: 19935661]
[EC 4.3.2.3 created 1972, modified 2014]
 
 


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