The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

EC 4.2.3.73     
Accepted name: valencene synthase
Reaction: (2E,6E)-farnesyl diphosphate = (+)-valencene + diphosphate
For diagram of eremophilane and spirovetivane sesquiterpenoid biosynthesis, click here
Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase (valencene-forming)
Comments: The recombinant enzyme from Vitis vinifera gave 49.5% (+)-valencene and 35.5% (-)-7-epi-α-selinene. Initial cyclization gives (+)-germacrene A in an enzyme bound form which is not released to the medium.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Lucker, J., Bowen, P. and Bohlmann, J. Vitis vinifera terpenoid cyclases: functional identification of two sesquiterpene synthase cDNAs encoding (+)-valencene synthase and (-)-germacrene D synthase and expression of mono- and sesquiterpene synthases in grapevine flowers and berries. Phytochemistry 65 (2004) 2649–2659. [PMID: 15464152]
[EC 4.2.3.73 created 2011]
 
 


Data © 2001–2017 IUBMB
Web site © 2005–2017 Andrew McDonald