EC |
4.2.3.73 |
Accepted name: |
valencene synthase |
Reaction: |
(2E,6E)-farnesyl diphosphate = (+)-valencene + diphosphate |
|
For diagram of eremophilane and spirovetivane sesquiterpenoid biosynthesis, click here |
Systematic name: |
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (valencene-forming) |
Comments: |
The recombinant enzyme from Vitis vinifera gave 49.5% (+)-valencene and 35.5% (-)-7-epi-α-selinene. Initial cyclization gives (+)-germacrene A in an enzyme bound form which is not released to the medium. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Lucker, J., Bowen, P. and Bohlmann, J. Vitis vinifera terpenoid cyclases: functional identification of two sesquiterpene synthase cDNAs encoding (+)-valencene synthase and (-)-germacrene D synthase and expression of mono- and sesquiterpene synthases in grapevine flowers and berries. Phytochemistry 65 (2004) 2649–2659. [DOI] [PMID: 15464152] |
|
[EC 4.2.3.73 created 2011] |
|
|
|
|