Accepted name: sesterfisherol synthase
Reaction: (2E,6E,10E,14E)-geranylfarnesyl diphosphate + H2O = sesterfisherol + diphosphate
Glossary: sesterfisherol = (3R,3aS,6S,6aR,7aR,10R,10aS,11aR)-3,6,7a,12-tetramethyl-10-(propan-2-yl)-2,3,3a,4,5,6,6a,7,7a,8,9,10,10a,11-tetradecahydrocyclopenta[4,5]cycloocta[f]inden-11a(1H)-ol
Other name(s): NfSS
Systematic name: (2E,6E,10E,14E)-geranylfarnesyl-diphosphate diphosphate-lyase (cyclizing, sesterfisherol-forming)
Comments: Isolated from the fungus Neosartorya fischeri.
1.  Ye, Y., Minami, A., Mandi, A., Liu, C., Taniguchi, T., Kuzuyama, T., Monde, K., Gomi, K. and Oikawa, H. Genome mining for sesterterpenes using bifunctional terpene synthases reveals a unified intermediate of di/sesterterpenes. J. Am. Chem. Soc. 137 (2015) 11846–11853. [PMID: 26332841]
[EC created 2017]

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