The Enzyme Database

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EC 4.2.3.175     
Accepted name: 10-epi-cubebol synthase
Reaction: (2E,6E)-farnesyl diphosphate + H2O = 10-epi-cubebol + diphosphate
For diagram of cadinane sesquiterpenoid biosynthesis, click here
Other name(s): sce6369
Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, 10-epi-cubebol-forming)
Comments: Isolated from the bacterium Sorangium cellulosum So ce56. The enzyme is also responsible for the formation of trace amounts of many other sesquiterpenes, mainly cadinanes and cubebanes.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB
References:
1.  Schifrin, A., Khatri, Y., Kirsch, P., Thiel, V., Schulz, S. and Bernhardt, R. A single terpene synthase is responsible for a wide variety of sesquiterpenes in Sorangium cellulosum Soce56. Org. Biomol. Chem. 14 (2016) 3385–3393. [DOI] [PMID: 26947062]
[EC 4.2.3.175 created 2017]
 
 


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