| EC |
4.2.3.15 |
| Accepted name: |
myrcene synthase |
| Reaction: |
geranyl diphosphate = myrcene + diphosphate |
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For diagram of monoterpenoid biosynthesis, click here |
| Glossary: |
myrcene = 7-methyl-3-methyleneocta-1,6-diene and is a monoterpenoid |
| Systematic name: |
geranyl-diphosphate diphosphate-lyase (myrcene-forming) |
| Comments: |
A recombinant enzyme (also known as a monoterpene synthase or cyclase) from the grand fir (Abies grandis) requires Mn2+ and K+ for activity. Mg2+ is essentially ineffective as the divalent metal ion cofactor. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 197462-59-2 |
| References: |
| 1. |
Bohlmann, J., Steele, C.L. and Croteau, R. Monoterpene synthases from grand fir (Abies grandis). cDNA isolation, characterization, and functional expression of myrcene synthase, (-)-(4S)-limonene synthase, and (-)-(1S,5S)-pinene synthase. J. Biol. Chem. 272 (1997) 21784–21792. [DOI] [PMID: 9268308] |
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| [EC 4.2.3.15 created 2000 as EC 4.1.99.9, transferred 2000 to EC 4.2.3.15] |
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