| EC |
4.2.3.110 |
| Accepted name: |
(+)-sabinene synthase |
| Reaction: |
geranyl diphosphate = (+)-sabinene + diphosphate |
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For diagram of thujane monoterpenoid biosynthesis, click here |
| Glossary: |
(+)-sabinene = (+)-thuj-4(10)-ene = (1R,5R)-1-isopropyl-4-methylenebicyclo[3.1.0]hexane |
| Other name(s): |
SS |
| Systematic name: |
geranyl-diphosphate diphosphate-lyase [cyclizing, (+)-sabinene-forming] |
| Comments: |
Isolated from Salvia officinalis (sage). The recombinant enzyme gave 63% (+)-sabinene, 21% γ-terpinene, and traces of other monoterpenoids. See EC 4.2.3.114 γ-terpinene synthase. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Wise, M.L., Savage, T.J., Katahira, E. and Croteau, R. Monoterpene synthases from common sage (Salvia officinalis). cDNA isolation, characterization, and functional expression of (+)-sabinene synthase, 1,8-cineole synthase, and (+)-bornyl diphosphate synthase. J. Biol. Chem. 273 (1998) 14891–14899. [DOI] [PMID: 9614092] |
| 2. |
Peters, R.J. and Croteau, R.B. Alternative termination chemistries utilized by monoterpene cyclases: chimeric analysis of bornyl diphosphate, 1,8-cineole, and sabinene synthases. Arch. Biochem. Biophys. 417 (2003) 203–211. [DOI] [PMID: 12941302] |
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| [EC 4.2.3.110 created 2012] |
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