The Enzyme Database

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EC 4.2.2.3     
Accepted name: poly(β-D-mannuronate) lyase
Reaction: Eliminative cleavage of polysaccharides containing β-D-mannuronate residues to give oligosaccharides with 4-deoxy-α-L-erythro-hex-4-enopyranuronosyl groups at their ends
Other name(s): alginate lyase I; alginate lyase; alginase I; alginase II; alginase; poly(β-D-1,4-mannuronide) lyase
Systematic name: poly[(1→4)-β-D-mannuronide] lyase
Links to other databases: BRENDA, EXPASY, IUBMB, KEGG, CAS registry number: 9024-15-1
References:
1.  Davidson, I.W., Lawson, C.J. and Sutherland, I.W. An alginate lysate from Azotobacter vinelandii phage. J. Gen. Microbiol. 98 (1977) 223–229. [PMID: 13144]
2.  Nakada, H.I. and Sweeny, P.C. Alginic acid degradation by eliminases from abalone hepatopancreas. J. Biol. Chem. 242 (1967) 845–851. [PMID: 6020438]
3.  Preiss, J. and Ashwell, G. Alginic acid metabolism in bacteria. I. Enzymatic formation of unsaturated oligosaccharides and 4-deoxy-L-erythro-5-hexoseulose uronic acid. J. Biol. Chem. 237 (1962) 309–316. [PMID: 14488584]
[EC 4.2.2.3 created 1965 as EC 4.2.99.4, transferred 1972 to EC 4.2.2.3, modified 1990]
 
 


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