The Enzyme Database

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EC 4.2.1.77     
Accepted name: trans-L-3-hydroxyproline dehydratase
Reaction: trans-3-hydroxy-L-proline = 1-pyrroline 2-carboxylate + H2O
Other name(s): trans-L-3-hydroxyproline hydro-lyase
Systematic name: trans-3-hydroxy-L-proline hydro-lyase (1-pyrroline-2-carboxylate-forming)
Comments: Highly specific.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Ramaswamy, S.G. Conversion of 3-hydroxyproline to proline in the rat requires reduced pyridine-nucleotides. Fed. Proc. 42 (1983) 2232.
2.  Visser, W.F., Verhoeven-Duif, N.M. and de Koning, T.J. Identification of a human trans-3-hydroxy-L-proline dehydratase, the first characterized member of a novel family of proline racemase-like enzymes. J. Biol. Chem. 287 (2012) 21654–21662. [PMID: 22528483]
[EC 4.2.1.77 created 1984]
 
 


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