citrate oxaloacetate-lyase (forming acetate from the pro-S carboxymethyl group of citrate)
The enzyme can be dissociated into components, two of which are identical with EC 184.108.40.206 (citrate CoA-transferase) and EC 220.127.116.11 (citryl-CoA lyase). EC 18.104.22.168, citrate lyase deacetylase, deacetylates and inactivates the enzyme.
Dagley, S. and Dawes, E.A. Citridesmolase: its properties and mode of action. Biochim. Biophys. Acta17 (1955) 177–184. [PMID: 13239657]
Dimroth, P., Loyal, R. and Eggerer, H. Characterization of the isolated transferase subunit of citrate lyase as a CoA-transferase. Evidence against a covalent enzyme-substrate intermediate. Eur. J. Biochem.80 (1977) 479–488. [PMID: 336371]