The Enzyme Database

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EC 4.1.3.32     
Accepted name: 2,3-dimethylmalate lyase
Reaction: (2R,3S)-2,3-dimethylmalate = propanoate + pyruvate
For diagram of nicotinate catabolism, click here
Other name(s): 2,3-dimethylmalate pyruvate-lyase; (2R,3S)-2,3-dimethylmalate pyruvate-lyase
Systematic name: (2R,3S)-2,3-dimethylmalate pyruvate-lyase (propanoate-forming)
Links to other databases: BRENDA, EXPASY, GTD, KEGG, MetaCyc, CAS registry number: 73562-28-4
References:
1.  Pirzer, P., Lill, U. and Eggerer, H. Nicotinic acid metabolism. 2,3-Dimethylmalate lyase. Hoppe-Seyler's Z. Physiol. Chem. 360 (1979) 1693–1702. [PMID: 527937]
2.  Alhapel, A., Darley, D.J., Wagener, N., Eckel, E., Elsner, N. and Pierik, A.J. Molecular and functional analysis of nicotinate catabolism in Eubacterium barkeri. Proc. Natl. Acad. Sci. USA 103 (2006) 12341–12346. [PMID: 16894175]
[EC 4.1.3.32 created 1981]
 
 


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