The Enzyme Database

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EC 4.1.1.121     
Accepted name: 3-oxoisoapionate-4-phosphate decarboxylase
Reaction: 3-oxoisoapionate 4-phosphate = L-erythrulose 1-phosphate + CO2
Glossary: 3-oxoisoapionate = 2,4-dihydroxy-2-(hydroxymethyl)-3-oxobutanoate
Other name(s): oiaX (gene name)
Systematic name: 3-oxoisoapionate 4-phosphate carboxy-lyase
Comments: The enzyme, characterized from several bacterial species, participates in the degradation of D-apionate. It belongs to the RuBisCO-like-protein (RLP) superfamily. Stereospecificity of 3-oxoisoapionate 4-phosphate has not been determined.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Carter, M.S., Zhang, X., Huang, H., Bouvier, J.T., Francisco, B.S., Vetting, M.W., Al-Obaidi, N., Bonanno, J.B., Ghosh, A., Zallot, R.G., Andersen, H.M., Almo, S.C. and Gerlt, J.A. Functional assignment of multiple catabolic pathways for D-apiose. Nat. Chem. Biol. 14 (2018) 696–705. [DOI] [PMID: 29867142]
[EC 4.1.1.121 created 2020]
 
 


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