The Enzyme Database

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EC 3.7.1.3     
Accepted name: kynureninase
Reaction: L-kynurenine + H2O = anthranilate + L-alanine
For diagram of tryptophan catabolism, click here
Systematic name: L-kynurenine hydrolase
Comments: A pyridoxal-phosphate protein. Also acts on 3′-hydroxy-L-kynurenine and some other (3-arylcarbonyl)-alanines.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9024-78-6
References:
1.  Jakoby, W.B. and Bonner, D.M. Kynureninase from Neurospora: purification and properties. J. Biol. Chem. 205 (1953) 699–707. [PMID: 13129248]
2.  Jakoby, W.B. and Bonner, D.M. Kynureninase from Neurospora: interactions of enzyme with substrates, coenzyme and amines. J. Biol. Chem. 205 (1953) 709–715. [PMID: 13129249]
3.  Knox, W.E. The relation of liver kynureninase to tryptophan metabolism in pyridoxine deficiency. Biochem. J. 53 (1953) 379–385. [PMID: 13032082]
4.  Wiss, O. and Weber, F. Die Reindarstellung der Kynureninase. Hoppe-Seyler's Z. Physiol. Chem. 304 (1956) 232–240.
[EC 3.7.1.3 created 1965]
 
 


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