The Enzyme Database

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EC 3.6.4.11     
Accepted name: nucleoplasmin ATPase
Reaction: ATP + H2O = ADP + phosphate
Systematic name: ATP phosphohydrolase (nucleosome-assembling)
Comments: An acidic nuclear protein that is active in the ATP-dependent assembly of nucleosome cores, in decondensation of sperm chromatin and in other histone-involving processes.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Laskey, R.A., Mills, A.D., Philpott, A., Leno, G.H., Dilworth, S.M. and Dingwall, C. The role of nucleoplasmin in chromatin assembly and disassembly. Phil. Trans. R. Soc. London B Biol. Sci. 339 (1993) 263–269. [PMID: 8098530]
2.  Cote, J., Quinn, J., Workman, J.L. and Peterson, C.L. Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex. Science 265 (1994) 53–60. [PMID: 8016655]
3.  Ito, T., Tyler, J.K., Bulger, M., Kobayashi, R. and Kadonaga, J.T. ATP-facilitated chromatin assembly with a nucleoplasmin-like protein from Drosophila melanogaster. J. Biol. Chem 271 (1996) 25041–25048. [PMID: 8798787]
[EC 3.6.4.11 created 2000]
 
 


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