The Enzyme Database

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Accepted name: guanine-transporting ATPase
Reaction: ATP + H2O + guanineout = ADP + phosphate + guaninein
Systematic name: ATP phosphohydrolase (guanine-importing)
Comments: ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. A eukaryotic enzyme that imports guanine and tryptophan (it contains a single ATP-binding site).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Dreesen, T.D., Johnson, D.H and Henikoff, S. The brown protein of Drosophila melanogaster is similar to the white protein and to components of active transport complexes. Mol. Cell Biol. 8 (1988) 5206–5215. [DOI] [PMID: 3149712]
2.  Tearle, R.G., Belote, J.M., McKeown, M., Baker, B.S. and Howells, A.J. Cloning and characterization of the scarlet gene of Drosophila melanogaster. Genetics 122 (1989) 595–606. [PMID: 2503416]
3.  Griffiths, J.K. and Sansom, C.E. The Transporter Factsbook, Academic Press, San Diego, 1998.
[EC created 2000]

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