The Enzyme Database

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EC 3.6.3.2     
Accepted name: Mg2+-importing ATPase
Reaction: ATP + H2O + Mg2+out = ADP + phosphate + Mg2+in
Systematic name: ATP phosphohydrolase (Mg2+-importing)
Comments: A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. This enzyme occurs in both Gram-positive and Gram-negative bacteria, and three types are known, designated as CorA, MgtA and MgtB. The CorA itself is not an ATPase but an Mg2+ transporter.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Tao, T., Snavely, M.D., Farr, S.G. and Maguire, M.E. Magnesium transport in Salmonella typhimurium: mtgA encodes a P-type ATPase and is regulated by Mg2+ in a manner similar to that of the mgtB P-type ATPase. J. Bacteriol. 177 (1995) 2654–2662. [PMID: 7751273]
2.  Smith, R.L., Szegedy, M.A., Kucharski, L.M., Walker, C., Wiet, R.M., Redpath, A., Kaczmarek, M.T. and Maguire, M.E. The CorA Mg2+ transport protein of Salmonella typhimurium. Mutagenesis of conserved residues in the third membrane domain identifies a Mg2+ pore. J. Biol. Chem. 273 (1998) 28663–28669. [PMID: 9786860]
[EC 3.6.3.2 created 2000, modified 2001]
 
 


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