The Enzyme Database

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EC 3.6.1.23     
Accepted name: dUTP diphosphatase
Reaction: dUTP + H2O = dUMP + diphosphate
Other name(s): deoxyuridine-triphosphatase; dUTPase; dUTP pyrophosphatase; desoxyuridine 5′-triphosphate nucleotidohydrolase; desoxyuridine 5′-triphosphatase
Systematic name: dUTP nucleotidohydrolase
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 37289-34-2
References:
1.  Bertani, L.E., Häggmark, A. and Reichard, P. Enzymatic synthesis of deoxyribonucleotides. II. Formation and interconversion of deoxyuridine phosphates. J. Biol. Chem. 238 (1963) 3407–3413. [PMID: 14085395]
2.  Giroir, L.E. and Deutsch, W.A. Drosophila deoxyuridine triphosphatase. Purification and characterization. J. Biol. Chem. 262 (1987) 130–134. [PMID: 3025197]
3.  Greenberg, G.R. and Somerville, R.L. Deoxyuridylate kinase activity and deoxyuridinetriphosphatase in Escherichia coli. Proc. Natl. Acad. Sci. USA 48 (1962) 247–257. [PMID: 13901467]
4.  Grindey, G.B. and Nichol, C.A. Mammalian deoxyuridine 5′-triphosphate pyrophosphatase. Biochim. Biophys. Acta 240 (1971) 180–183. [PMID: 5105331]
[EC 3.6.1.23 created 1972]
 
 


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