| EC |
3.6.1.23 |
| Accepted name: |
dUTP diphosphatase |
| Reaction: |
dUTP + H2O = dUMP + diphosphate |
| Other name(s): |
deoxyuridine-triphosphatase; dUTPase; dUTP pyrophosphatase; desoxyuridine 5′-triphosphate nucleotidohydrolase; desoxyuridine 5′-triphosphatase |
| Systematic name: |
dUTP nucleotidohydrolase |
| Links to other databases: |
BRENDA, EXPASY, KEGG, METACYC, PDB, CAS registry number: 37289-34-2 |
| References: |
| 1. |
Bertani, L.E., Häggmark, A. and Reichard, P. Enzymatic synthesis of deoxyribonucleotides. II. Formation and interconversion of deoxyuridine phosphates. J. Biol. Chem. 238 (1963) 3407–3413. [PMID: 14085395] |
| 2. |
Giroir, L.E. and Deutsch, W.A. Drosophila deoxyuridine triphosphatase. Purification and characterization. J. Biol. Chem. 262 (1987) 130–134. [PMID: 3025197] |
| 3. |
Greenberg, G.R. and Somerville, R.L. Deoxyuridylate kinase activity and deoxyuridinetriphosphatase in Escherichia coli. Proc. Natl. Acad. Sci. USA 48 (1962) 247–257. [PMID: 13901467] |
| 4. |
Grindey, G.B. and Nichol, C.A. Mammalian deoxyuridine 5′-triphosphate pyrophosphatase. Biochim. Biophys. Acta 240 (1971) 180–183. [PMID: 5105331] |
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| [EC 3.6.1.23 created 1972] |
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