The Enzyme Database

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EC 3.5.99.4     
Accepted name: N-isopropylammelide isopropylaminohydrolase
Reaction: N-isopropylammelide + H2O = cyanuric acid + isopropylamine
Glossary: cyanuric acid = 1,3,5-triazine-2,4,6(1H,3H,5H)-trione = 2,4,6-trihydroxy-s-triazine
Other name(s): AtzC
Systematic name: N-isopropylammelide isopropylaminohydrolase
Comments: Involved in a pathway by which the herbicide atrazine, 2-chloro-4-(ethylamino)-6-(isopopylamino)-1,3,5-triazine, is degraded in bacteria via N-isopropylammelide, 2,4-dihydroxy-6-(isopropylamino)-1,3,5-triazine.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, UM-BBD, CAS registry number: 203810-02-0
References:
1.  Sadowsky, M.J., Tong, Z., de Souza, M. and Wackett, L.P. AtzC is a new member of the amidohydrolase protein superfamily and is homologous to other atrazine-metabolizing enzymes. J. Bacteriol. 180 (1998) 152–158. [PMID: 9422605]
[EC 3.5.99.4 created 2000]
 
 


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