| EC |
3.5.4.6 |
| Accepted name: |
AMP deaminase |
| Reaction: |
AMP + H2O = IMP + NH3 |
|
For diagram of AMP catabolism, click here |
| Other name(s): |
adenylic acid deaminase; AMP aminase; adenylic deaminase; adenylate deaminase; 5-AMP deaminase; adenosine 5-monophosphate deaminase; 5-adenylate deaminase; adenyl deaminase; 5-adenylic acid deaminase; adenosine monophosphate deaminase; adenylate aminohydrolase; adenylate desaminase; adenosine 5-phosphate aminohydrolase; 5-adenylate deaminase |
| Systematic name: |
AMP aminohydrolase |
| Comments: |
cf. EC 3.5.4.17 adenosine-phosphate deaminase. |
| Links to other databases: |
BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9025-10-9 |
| References: |
| 1. |
Kalckar, H.M. Differential spectrophotometry of purine compounds by means of specific enzymes. III. Studies of the enzymes of purine metabolism. J. Biol. Chem. 167 (1947) 461–475. [PMID: 20285041] |
| 2. |
Lee, Y.-P. 5′-Adenylic acid deaminase. I. Isolation of the crystalline enzyme from rabbit skeletal muscle. J. Biol. Chem. 227 (1957) 987–992. [PMID: 13463019] |
| 3. |
Lee, Y.-P. 5′-Adenylic acid deaminase. II. Homogeneity and physicochemical properties. J. Biol. Chem. 227 (1957) 993–998. [PMID: 13463020] |
| 4. |
Lee, Y.-P. 5′-Adenylic acid deaminase. III. Properties and kinetic studies. J. Biol. Chem. 227 (1957) 999–1007. [PMID: 13463021] |
| 5. |
Mendicino, J. and Muntz, J.A. The activating effect of adenosine triphosphate on brain adenylic deaminase. J. Biol. Chem. 233 (1958) 178–183. [PMID: 13563464] |
| 6. |
Turner, D.H. and Turner, J.F. Adenylic deaminase of pea seeds. Biochem. J. 79 (1961) 143–147. [PMID: 13778717] |
| 7. |
Weil-Malherbe, W. and Green, R.H. Ammonia formation in brain. 2. Brain adenylic deaminase. Biochem. J. 61 (1955) 218–224. [PMID: 13260201] |
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| [EC 3.5.4.6 created 1961] |
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