The Enzyme Database

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EC 3.5.4.46     
Accepted name: cAMP deaminase
Reaction: 3′,5′-cyclic AMP + H2O = 3′,5′-cyclic IMP + NH3
Other name(s): cyclic adenylate deaminase; CadD
Systematic name: 3′,5′-cyclic AMP aminohydrolase
Comments: Requires Zn2+. The enzyme, isolated from the bacterium Leptospira interrogans, is specific for cAMP.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Goble, A.M., Feng, Y., Raushel, F.M. and Cronan, J.E. Discovery of a cAMP deaminase that quenches cyclic AMP-dependent regulation. ACS Chem. Biol. 8 (2013) 2622–2629. [DOI] [PMID: 24074367]
[EC 3.5.4.46 created 2017]
 
 


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