The Enzyme Database

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EC 3.5.4.12     
Accepted name: dCMP deaminase
Reaction: dCMP + H2O = dUMP + NH3
Other name(s): deoxycytidylate deaminase; deoxy-CMP-deaminase; deoxycytidylate aminohydrolase; deoxycytidine monophosphate deaminase; deoxycytidine-5′-phosphate deaminase; deoxycytidine-5′-monophosphate aminohydrolase
Systematic name: dCMP aminohydrolase
Comments: Also acts on some 5-substituted dCMPs.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9026-92-0
References:
1.  Scarano, E. The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. I. The enzymatic deamination of deoxycytidine 5′-phosphate and of 5-methyldeoxycytidine 5-methyldeoxycytidine 5′-phosphate. J. Biol. Chem. 235 (1960) 706–713. [PMID: 14442222]
2.  Scarano, E., Bonaduce, L. and de Petrocellis, B. The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. II. Purification and properties of a 6-aminopyrimidine deoxyribonucleoside 5′-phosphate deaminase from unfertilized eggs of sea urchin. J. Biol. Chem. 235 (1960) 3556–3561. [PMID: 13747062]
3.  Sergott, R.C., Debeer, L.J. and Bessman, M.J. On the regulation of a bacterial deoxycytidylate deaminase. J. Biol. Chem. 246 (1971) 7755–7758. [PMID: 5002683]
[EC 3.5.4.12 created 1965]
 
 


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