| EC |
3.5.4.10 |
| Accepted name: |
IMP cyclohydrolase |
| Reaction: |
IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide |
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For diagram of purine biosynthesis (late stages), click here |
| Other name(s): |
inosinicase; inosinate cyclohydrolase; IMP 1,2-hydrolase (decyclizing) |
| Systematic name: |
IMP 1,2-hydrolase (ring-opening) |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9013-81-4 |
| References: |
| 1. |
Flaks, J.G., Erwin, M.J. and Buchanan, J.M. Biosynthesis of the purines. XVIII. 5-Amino-1-ribosyl-4-imidazolecarboxamide 5′-phosphate transformylase and inosinicase. J. Biol. Chem. 229 (1957) 603–612. [PMID: 13502325] |
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| [EC 3.5.4.10 created 1961, modified 2000] |
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