The Enzyme Database

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EC 3.5.1.43     
Accepted name: peptidyl-glutaminase
Reaction: α-N-peptidyl-L-glutamine + H2O = α-N-peptidyl-L-glutamate + NH3
Other name(s): peptidoglutaminase I; peptideglutaminase; peptidoglutaminase
Systematic name: peptidyl-L-glutamine amidohydrolase
Comments: Specific for the hydrolysis of the γ-amide of glutamine substituted at the α-amino group, e.g., glycyl-L-glutamine, N-acetyl-L-glutamine and L-leucylglycyl-L-glutamine.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 37228-70-9
References:
1.  Kikuchi, M., Hayashida, H., Nakano, E. and Sakaguchi, K. Peptidoglutaminase. Enzymes for selective deamidation of γ-amide of peptide-bound glutamine. Biochemistry 10 (1971) 1222–1229. [PMID: 4928623]
[EC 3.5.1.43 created 1976]
 
 


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