The Enzyme Database

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EC 3.5.1.23     
Accepted name: ceramidase
Reaction: a ceramide + H2O = a carboxylate + sphingosine
Glossary: a ceramide = an N-acylsphingosine
Other name(s): acylsphingosine deacylase; glycosphingolipid ceramide deacylase
Systematic name: N-acylsphingosine amidohydrolase
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 37289-06-8
References:
1.  Nilsson, A. The presence of spingomyelin- and ceramide-cleaving enzymes in the small intestinal tract. Biochim. Biophys. Acta 176 (1969) 339–347. [PMID: 5775951]
2.  Yavin, E. and Gatt, S. Enzymatic hydrolysis of sphingolipids. 8. Further purification and properties of rat brain ceramidase. Biochemistry 8 (1969) 1692–1698. [PMID: 5805303]
[EC 3.5.1.23 created 1972, modified 1990]
 
 


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