| EC |
3.4.24.6 |
| Accepted name: |
leucolysin |
| Reaction: |
Cleavage of Phe1┼Val, His5┼Leu, Ala14┼Leu, Gly20┼Glu, Gly23┼Phe and Phe24┼Phe bonds in insulin B chain as well as N-blocked dipeptides |
| Other name(s): |
Leucostoma neutral proteinase; Leucostoma peptidase A |
| Comments: |
From the venom of the western cottonmouth moccasin snake (Agkistrodon piscivorus leucostoma). |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 72561-03-6 |
| References: |
| 1. |
Wagner, F.W., Spiekerman, A.M. and Prescott, J.M. Leucostoma peptidase A. Isolation and physical properties. J. Biol. Chem. 243 (1968) 4486–4493. [PMID: 5684005] |
| 2. |
Spiekerman, A.M., Fredericks, K.K., Wagner, F.W. and Prescott, J.M. Leucostoma peptidase A: a metalloprotease from snake venom. Biochim. Biophys. Acta 293 (1973) 464–475. [DOI] [PMID: 4711816] |
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| [EC 3.4.24.6 created 1978] |
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