| EC |
3.4.24.45 |
| Accepted name: |
atrolysin F |
| Reaction: |
Cleavage of Val2┼Asn, Gln4┼His, Leu6┼Cys, His10┼Leu, Ala14┼Leu and Tyr16┼Leu bonds in insulin B chain |
| Other name(s): |
Crotalus atrox metalloendopeptidase; hemorrhagic toxin f; Crotalus atrox metalloendopeptidase f |
| Comments: |
A 64 kDa hemorrhagic endopeptidase from the venom of the western diamondback rattlesnake (Crotalus atrox) that digests the γ chain of fibrinogen. Immunologically distinct from EC 3.4.24.1, atrolysin A. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 172306-52-4 |
| References: |
| 1. |
Nikai, T., Mori, N., Kishida, M., Sugihara, H. and Tu, A.T. Isolation and biochemical characterization of hemorrhagic toxin f from the venom of Crotalus atrox (western diamondback rattlesnake). Arch. Biochem. Biophys. 231 (1984) 309–319. [DOI] [PMID: 6375570] |
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| [EC 3.4.24.45 created 1992] |
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