The Enzyme Database

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EC 3.4.24.43     
Accepted name: atroxase
Reaction: Cleavage of His5┼Leu, Ser9┼His, His10┼Leu, Ala14┼Leu and Tyr16┼Leu of insulin B chain
Comments: A nonhemorrhagic endopeptidase from the venom of the western diamondback rattlesnake (Crotalus atrox) that cleaves fibrinogen. In peptidase family M12 (astacin family)
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, CAS registry number: 181186-94-7
References:
1.  Willis, T.W. and Tu, A.T. Purification and biochemical characterization of atroxase, a nonhemorrhagic fibrinolytic protease from western diamondback rattlesnake venom. Biochemistry 27 (1988) 4769–4777. [PMID: 3167016]
[EC 3.4.24.43 created 1992]
 
 


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