| EC |
3.4.24.22 |
| Accepted name: |
stromelysin 2 |
| Reaction: |
Similar to stromelysin 1, but action on collagen types III, IV and V is weak |
| Other name(s): |
matrix metalloproteinase 10; transin 2; proteoglycanase 2 |
| Comments: |
In peptidase family M10 (interstitial collagenase family). Digests gelatin types I, III, IV, V, fibronectin and proteoglycan |
| Links to other databases: |
BRENDA, EXPASY, KEGG, METACYC, MEROPS, PDB, CAS registry number: 140610-48-6 |
| References: |
| 1. |
Breathnach, R., Matrisian, L.M., Gesnel, M.-C. and Leroy, P. Sequences coding for part of oncogene-induced transin are highly conserved in a related rat gene. Nucleic Acids Res. 15 (1987) 1139–1151. [PMID: 3547333] |
| 2. |
Muller, D., Quantin, B., Gesnel, M.-C., Millon-Collard, R., Abecassis, J. and Breathnach, R. The collagenase gene family in humans consists of at least four members. Biochem. J. 253 (1988) 187–192. [PMID: 2844164] |
| 3. |
Nicholson, R., Murphy, G. and Breathnach, R. Human and rat malignant-tumor-associated mRNAs encode stromelysin-like metalloproteinases. Biochemistry 28 (1989) 5195–5203. [PMID: 2548603] |
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| [EC 3.4.24.22 created 1992] |
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