The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

EC 3.4.24.22     
Accepted name: stromelysin 2
Reaction: Similar to stromelysin 1, but action on collagen types III, IV and V is weak
Other name(s): matrix metalloproteinase 10; transin 2; proteoglycanase 2
Comments: In peptidase family M10 (interstitial collagenase family). Digests gelatin types I, III, IV, V, fibronectin and proteoglycan
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, PDB, CAS registry number: 140610-48-6
References:
1.  Breathnach, R., Matrisian, L.M., Gesnel, M.-C. and Leroy, P. Sequences coding for part of oncogene-induced transin are highly conserved in a related rat gene. Nucleic Acids Res. 15 (1987) 1139–1151. [PMID: 3547333]
2.  Muller, D., Quantin, B., Gesnel, M.-C., Millon-Collard, R., Abecassis, J. and Breathnach, R. The collagenase gene family in humans consists of at least four members. Biochem. J. 253 (1988) 187–192. [PMID: 2844164]
3.  Nicholson, R., Murphy, G. and Breathnach, R. Human and rat malignant-tumor-associated mRNAs encode stromelysin-like metalloproteinases. Biochemistry 28 (1989) 5195–5203. [PMID: 2548603]
[EC 3.4.24.22 created 1992]
 
 


Data © 2001–2014 IUBMB
Web site © 2005–2014 Andrew McDonald