The Enzyme Database

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EC 3.4.22.26     
Accepted name: cancer procoagulant
Reaction: Specific cleavage of Arg┼Ile bond in Factor X to form Factor Xa
Comments: Apparently produced only by malignant and fetal cells
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 109456-80-6
References:
1.  Falanga, A. and Gordon, S.G. Isolation and characterization of cancer procoagulant: a cysteine proteinase from malignant tissue. Biochemistry 24 (1985) 5558–5567. [PMID: 3935163]
2.  Falanga, A., Shaw, E., Donati, M.B., Consonni, R., Barbui, T. and Gordon, S. Inhibition of cancer procoagulant by peptidyl diazomethyl ketones and peptidyl sulfonium salts. Thromb. Res. 54 (1989) 389–398. [PMID: 2772865]
[EC 3.4.22.26 created 1992]
 
 


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