The Enzyme Database

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Accepted name: actinidain
Reaction: Similar to that of papain
Other name(s): actinidin; Actinidia anionic protease; proteinase A2 of Actinidia chinensis
Comments: From the kiwi fruit or Chinese gooseberry (Actinidia chinensis). In peptidase family C1 (papain family)
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, PDB, CAS registry number: 39279-27-1
1.  Baker, E.N., Boland, M.J., Calder, P.C. and Hardman, M.J. The specificity of actinidin and its relationship to the structure of the enzyme. Biochim. Biophys. Acta 616 (1980) 30–34. [PMID: 7002215]
2.  Kamphuis, I.G., Drenth, J. and Baker, E.N. Thiol proteases. Comparative studies based on the high-resolution structures of papain and actinidin, and on amino acid sequence information for cathepsins B and H, and stem bromelain. J. Mol. Biol. 182 (1985) 317–329. [PMID: 3889350]
3.  Baker, E.N. and Drenth, J. The thiol proteases: stucture and mechanism. In: Jurnak, F.A. and McPherson, A. (Eds), Biological Macromolecules and Assemblies: Active Sites of Enzymes, vol. 3, John Wiley and Sons, New York, 1987, pp. 314–368.
[EC created 1978]

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