The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

EC 3.4.21.80     
Accepted name: streptogrisin A
Reaction: Hydrolysis of proteins with specificity similar to chymotrypsin
Other name(s): Streptomyces griseus protease A; protease A; proteinase A; Streptomyces griseus proteinase A; Streptomyces griseus serine proteinase 3; Streptomyces griseus serine proteinase A
Comments: From Streptomyces griseus. A component of Pronase, in family S1 (trypsin family). Not inhibited by Tos-Phe-CH2Cl or ovomucoid
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, CAS registry number: 55326-50-6
References:
1.  Johnson, P. and Smillie, L.B. The disulfide bridge sequences of a serine protease of wide specificity from Streptomyces griseus. Can. J. Biochem. 49 (1971) 548–562. [PMID: 5575653]
2.  Sielecki, A.R., Hendrickson, W.A., Broughton, C.G., Delbaere, L.T.J., Brayer, G.D. and James, M.N.G. Protein structure refinement: Streptomyces griseus serine protease A at 1.8 Å resolution. J. Mol. Biol. 134 (1979) 781–804. [PMID: 119870]
3.  James, M.N.G., Sielecki, A.R., Brayer, G.D., Delbaere, L.T.J. and Bauer, C.-A. Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 Å resolution. J. Mol. Biol. 144 (1980) 43–88. [PMID: 6783761]
4.  Delbaere, L.T.J. and Brayer, G.D. The 1.8 Å structure of the complex between chymostatin and Streptomyces griseus protease A. A model for serine protease catalytic tetrahedral intermediates. J. Mol. Biol. 183 (1985) 89–103. [PMID: 3892018]
5.  Henderson, G., Krygsman, P., Liu, C.J., Davey, C.C. and Malek, L.T. Characterization and structure of genes for proteases A and B from Streptomyces griseus. J. Bacteriol. 169 (1987) 3778–3784. [PMID: 3112129]
[EC 3.4.21.80 created 1993]
 
 


Data © 2001–2017 IUBMB
Web site © 2005–2017 Andrew McDonald