| EC |
3.4.21.77 |
| Accepted name: |
semenogelase |
| Reaction: |
Preferential cleavage: -Tyr┼ |
| Other name(s): |
prostate-specific antigen; α-seminoprotein; seminin; P-30 antigen; antigen (human clone HPSA-1 prostate-specific protein moiety reduced); γ-seminoglycoprotein (human protein moiety reduced); γ-SM; antigen PSA (human prostate-specific); human glandular kallikrein; antigen PSA (human clone 5P1 protein moiety reduced) |
| Comments: |
A peptidase of family S1 (trypsin family) from seminal plasma. Slowly inhibited by α1-antichymotrypsin |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, PDB, CAS registry number: 110157-83-0, 95829-41-7 |
| References: |
| 1. |
Digby, M., Zhang, X.-Y. and Richards, R.I. Human prostate specific antigen (PSA) gene: structure and linkage to the kallikrein-like gene, hGK-1. Nucleic Acids Res. 15 (1989) 2137. [DOI] [PMID: 2467258] |
| 2. |
Christensson, A., Laurell, C.-B. and Lilja, H. Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors. Eur. J. Biochem. 194 (1990) 755–763. [DOI] [PMID: 1702714] |
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| [EC 3.4.21.77 created 1993] |
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