| EC |
3.4.21.65 |
| Accepted name: |
thermomycolin |
| Reaction: |
Rather nonspecific hydrolysis of proteins. Preferential cleavage: Ala┼, Tyr┼, Phe┼ in small molecule substrates |
| Other name(s): |
thermomycolase |
| Comments: |
A peptidase of family S8 (subtilisin family) from the thermophilic fungus Malbranchea pulchella var. sulfurea containing Cys, but not inhibited by p-mercuribenzoate. Very thermostable. Formerly included in EC 3.4.21.14 |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, CAS registry number: 52233-31-5 |
| References: |
| 1. |
Gaucher, G.M. and Stevenson, K.J. Thermomycolin. Methods Enzymol. 45 (1976) 415–433. [PMID: 1012007] |
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| [EC 3.4.21.65 created 1992 (EC 3.4.21.14 created 1961 as EC 3.4.4.16, transferred 1972 to EC 3.4.21.14, modified 1986, part incorporated 1992)] |
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