Known from Escherichia coli and Salmonella typhimurium. A zinc metallopeptidase in peptidase family M3 (thimet oligopeptidase family). Ac-Ala┼Ala-Ala is a good test substrate . Inhibited by captopril, as is peptidyl-dipeptidase A. Formerly EC 220.127.116.11, and included in EC 18.104.22.168, peptidyl-dipeptidase A.
Yaron, A. Dipeptidyl carboxypeptidase from Escherichia coli. Methods Enzymol.45 (1976) 599–610. [DOI] [PMID: 13271]
Henrich, B., Becker, S., Schroeder, U. and Plapp, R. dcp gene of Escherichia coli: cloning, sequencing, transcript mapping, and characterization of the gene product. J. Bacteriol.175 (1993) 7290–7300. [DOI] [PMID: 8226676]
Conlin, C.A. and Miller, C.G. Oligopeptidase A and peptidyl-dipeptidase of Escherichia and Salmonella. Methods Enzymol.248 (1995) 567–579. [PMID: 7674945]
[EC 22.214.171.124 created 1981 as EC 126.96.36.199, modified 1989, transferred 1996 to EC 188.8.131.52]