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Your query returned 1 entry. Printable version
EC | 3.2.2.9 | ||||||||||||
Accepted name: | adenosylhomocysteine nucleosidase | ||||||||||||
Reaction: | (1) S-adenosyl-L-homocysteine + H2O = S-(5-deoxy-D-ribos-5-yl)-L-homocysteine + adenine (2) 5′-deoxyadenosine + H2O = 5-deoxy-D-ribose + adenine (3) S-methyl-5′-thioadenosine + H2O = 5-(methylsulfanyl)-D-ribose + adenine |
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For diagram of autoinducer AI-2 biosynthesis, click here and for diagram of the methionine-salvage pathway, click here | |||||||||||||
Other name(s): | S-adenosylhomocysteine hydrolase (ambiguous); S-adenosylhomocysteine nucleosidase; 5′-methyladenosine nucleosidase; S-adenosylhomocysteine/5′-methylthioadenosine nucleosidase; AdoHcy/MTA nucleosidase; MTN2 (gene name); mtnN (gene name) | ||||||||||||
Systematic name: | S-adenosyl-L-homocysteine homocysteinylribohydrolase | ||||||||||||
Comments: | This enzyme, found in bacteria and plants, acts on three different substrates. It is involved in the S-adenosyl-L-methionine (SAM, AdoMet) cycle, which recycles S-adenosyl-L-homocysteine back to SAM, and in salvage pathways for 5′-deoxyadenosine and S-methyl-5′-thioadenosine, which are produced from SAM during the action of many enzymes. cf. the plant enzyme EC 3.2.2.16, methylthioadenosine nucleosidase. | ||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9055-10-1 | ||||||||||||
References: |
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