| EC |
3.2.1.130 |
| Accepted name: |
glycoprotein endo-α-1,2-mannosidase |
| Reaction: |
Hydrolysis of the terminal α-D-glucosyl-(1,3)-D-mannosyl unit from the GlcMan9(GlcNAc)2 oligosaccharide component of the glycoprotein produced in the Golgi membrane |
| Other name(s): |
glucosylmannosidase; endo-α-D-mannosidase; endo-α-mannosidase; endomannosidase; glucosyl mannosidase |
| Systematic name: |
glycoprotein glucosylmannohydrolase |
| Comments: |
Involved in the synthesis of glycoproteins. |
| Links to other databases: |
BRENDA, EXPASY, IUBMB, KEGG, CAS registry number: 108022-16-8 |
| References: |
| 1. |
Lubas, W.A. and Spiro, R.G. Golgi endo-α-D-mannosidase from rat liver, a novel N-linked carbohydrate unit processing enzyme. J. Biol. Chem. 262 (1987) 3775–3781. [PMID: 3818665] |
| 2. |
Tulsiani, D.R.P., Coleman, V.P. and Touster, O. Asparagine-linked glycoprotein biosynthesis in rat brain: identification of glucosidase I, glucosidase II, and endomannosidase (glucosyl mannosidase). Arch. Biochem. Biophys. 277 (1990) 114–121. [PMID: 2407194] |
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| [EC 3.2.1.130 created 1990] |
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