The Enzyme Database

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EC 3.2.1.130     
Accepted name: glycoprotein endo-α-1,2-mannosidase
Reaction: Hydrolysis of the terminal α-D-glucosyl-(1,3)-D-mannosyl unit from the GlcMan9(GlcNAc)2 oligosaccharide component of the glycoprotein produced in the Golgi membrane
Other name(s): glucosylmannosidase; endo-α-D-mannosidase; endo-α-mannosidase; endomannosidase; glucosyl mannosidase
Systematic name: glycoprotein glucosylmannohydrolase
Comments: Involved in the synthesis of glycoproteins.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 108022-16-8
References:
1.  Lubas, W.A. and Spiro, R.G. Golgi endo-α-D-mannosidase from rat liver, a novel N-linked carbohydrate unit processing enzyme. J. Biol. Chem. 262 (1987) 3775–3781. [PMID: 3818665]
2.  Tulsiani, D.R.P., Coleman, V.P. and Touster, O. Asparagine-linked glycoprotein biosynthesis in rat brain: identification of glucosidase I, glucosidase II, and endomannosidase (glucosyl mannosidase). Arch. Biochem. Biophys. 277 (1990) 114–121. [PMID: 2407194]
[EC 3.2.1.130 created 1990]
 
 


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